About the Opportunity

Job Summary:

In the New England Inflammation and Tissue Protection Institute (NEITPI), under the direction of Dr. Michail Sitkovsky, the Laboratory Technician will independently perform basic or applied research of higher scope and complexity. In addition to standard responsibilities of a Laboratory Technician (managing lab inventory, safety protocols, hazardous waste, general lab maintenance), the Technician will be responsible for conducting research experiments with CAR-T cells and polyclonal T cells using in vitro and in vivo cancer immunotherapy models. Bench level experience with human or mouse T cells in tumor-bearing hosts is highly desirable. The technician should have significant experience in mammalian cell culture and performing basic immunological research. Experience in cancer immunotherapy or infectious disease models is preferred. The technician will utilize flow cytometry, cell sorting, immunofluorescence, ELISA, qRT-PCR, and cell-based assays to evaluate novel treatment strategies during in vivo mouse cancer immunotherapy models. Experience in animal handling and murine cancer immunotherapy protocols is a plus. The technician will provide functional and administrative supervision of graduate/undergraduate students as well as attend meetings and present research. The incumbent will also be encouraged to publish findings of main research projects in peer-reviewed journals.

Responsibilities:

• Perform research ___55______ 45% 30 – 60%

• Write for publication __ 10 15% 10 – 30%

• General lab maintenance ___15 15% 5 – 25%

• Assist graduate students ___10______ 15% 5 – 25%

• Inventory and administration ___10_____ 10% 5 – 15%

Qualifications:

Must have a B.S. or equivalent and 2+ years laboratory experience. This experience should demonstrate the ability to plan and execute research projects; previous experience with mammalian cell culture, flow cytometry (and Flowjo analysis software), ELISA, immunohistochemistry, RT-PCR, fluorescent microscopy, animal handling/injection, in vivo tumor immunology assays.

Please use the space below to identify specific requirements for this position.

• Past experience might in the generation and analysis of anti-tumor T cells [polyclonal T cells and chimeric antigen receptor (CAR) T cells] is a plus
• Use of flow cytometry (and Flowjo analysis software) is important along with in vivo mouse cancer immunotherapy models.
• Mammalian cell culture including co-culturing of immune cells and tumor cells is highly desirable.
• Analysis of tumor microenvironment on the level of cytokines and chemokines.
• Experience in methods and models of cancer immunotherapies

Position Type

Additional Information

Northeastern University considers factors such as candidate work experience, education and skills when extending an offer.

Northeastern University is an equal opportunity employer, seeking to recruit and support a broadly diverse community of faculty and staff. Northeastern values and celebrates diversity in all its forms and strives to foster an inclusive culture built on respect that affirms inter-group relations and builds cohesion.

All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, religion, color, national origin, age, sex, sexual orientation, disability status, or any other characteristic protected by applicable law.

To learn more about Northeastern University’s commitment and support of diversity and inclusion, please see www.northeastern.edu/diversity.